Lactobacillus rhamnosus Enhances the Immunological Antitumor Effect of 5-Fluorouracil against Colon Cancer
نویسندگان
چکیده
منابع مشابه
Hydrogen–water enhances 5-fluorouracil-induced inhibition of colon cancer
Oxidative stress is involved in cancer development. Hydrogen (H2) is a potent antioxidant and exhibits anti-inflammatory and potentially anticancer-like activities. This study aimed to investigate the role of H2 incombination with 5-fluorouracil (5-FU) in cancer treatment both in vitro and in vivo using the colon 26 cell line. The survival rate was determined using the Kaplan-Meier survival tes...
متن کاملmethoxyamine enhances 5-fluorouracil-induced radiosensitization in colon cancer cell line ht29
objective: the purpose of this study was to observe the effects of methoxyamine (mx) on the cytotoxic effects and dna damage caused by 5-fluorouoracil (5-fu), in combination with gamma-rays in human colon cancer cell line. materials and methods: in this experimental study, ht29 cells were cultured as a monolayer and treated with different concentrations of 5-fu along with 1 mm mx for 24 h. afte...
متن کاملThe Study of Expression of Casp3/Bax Genes in HT29 Colon Cancer Cell Line with Lactobacillus rhamnosus Co-Culturing
Introduction: Colon cancer has spread to developed countries. Probiotic bacteria can play an important role in reducing cancer and treating colon cancer. The aim of this study was to determine the effect of adjacent bovine Lactobacillus rhamnose culture on the expression of casp3 and bax genes in cancer cell. Materials & Methods: In this experimental study after bacterial culture, supernatan...
متن کاملMolecular mechanisms of sequence-dependent antitumor effects of SN-38 and 5-fluorouracil combination therapy against colon cancer cells.
BACKGROUND The aim of this study was to clarify the molecular mechanisms of the sequence-dependent antitumor activity of SN-38 and 5-fluorouracil (5-FU) against colon cancer cells. MATERIALS AND METHODS KM12SM and HCT116 colon cancer cells were exposed to 5-FU and/or SN-38 in various conditions. The nature of interactions was determined by median-effect analysis. Cell cycle, apoptosis, and ex...
متن کاملInfliximab enhances the therapeutic effects of 5-fluorouracil resulting in tumor regression in colon cancer
Colon cancer (CC) is among the most common malignant diseases with a dismal survival. Tumor necrosis factor-alpha (TNF-α) has been identified as a therapeutic target in various cancers, and anti-TNF-α treatment has shown promising effects in different cancer models. However, if TNF-α can be targeted in CC, the therapeutic values of anti-TNF-α treatment in CC remain unknown. Our study indicated ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pakistan Journal of Biological Sciences
سال: 2019
ISSN: 1028-8880
DOI: 10.3923/pjbs.2019.597.606